Today the oral rout is the preferred rout of drug administration because of low cost of therapy and ease of administration. Oral controlled release stomach specific system is a promising delivery system for a drug candidate having limited absorption window, low solubility, local action in stomach, and those drugs which degrades in intestinal fluid. This review covers the detailed scenario related to stomach specific drug delivery system with their advantages over the conventional drug delivery system and also limitation. The term “Gastroretentive Drug Delivery System (GRDDS) may also be used for stomach specific drug delivery system. Various types of techniques are employed for development of such dosages form. This review also focus on formulation aspect of floating drug delivery system and some floating drug delivery system, available in market, are also enlisted. The purpose of this comprehensive review is to provide basic knowledge of GRDDS.
Loading....